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Heterotrimeric G protein : ウィキペディア英語版 | Heterotrimeric G protein
"G protein" usually refers to the membrane-associated heterotrimeric G proteins, sometimes referred to as the ''"large" G proteins'' (as opposed to the subclass of smaller, monomeric small GTPases) . These proteins are activated by G protein-coupled receptors and are made up of ''alpha'' (α), ''beta'' (β) and ''gamma'' (γ) subunits, the latter two referred to as the beta-gamma complex. There are four main families of G proteins: Gi/Go, Gq, Gs, and G12. ==Alpha subunits== (詳細はalpha-helical domain. There exist at least 20 different Gα subunits, which are separated into four main families. This nomenclature is based on their sequence homologies:
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